In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine

Author:

Howell G,West L,Jenkins C,Lineberry B,Yokum D,Rockhold R

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference39 articles.

1. Kay GG, Harris AG: Loratadine: a non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation. Clin Exp Allergy. 1999, 29 Suppl 3: 147-150. 10.1046/j.1365-2222.1999.0290S3147.x.

2. DuBuske LM: Second-generation antihistamines: the risk of ventricular arrhythmias. Clin Ther. 1999, 21: 281-295. 10.1016/S0149-2918(00)88286-7.

3. Anthes JC, Gilchrest H, Richard C, Eckel S, Hesk D, West REJ, Williams SM, Greenfeder S, Billah M, Kreutner W, Egan RE: Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor. Eur J Pharmacol. 2002, 449: 229-237. 10.1016/S0014-2999(02)02049-6.

4. Handley DA, McCullough JR, Fang Y, Wright SE, Smith ER: Descarboethoxyloratadine, a metabolite of loratadine, is a superior antihistamine. Ann Allergy Asthma Immunol. 1997, 78: P164-

5. Cardelus I, Puig J, Bou J, Jauregui J, Llenas J, Fernandez AG, Palacios JM: Xerostomia and mydriasis, two muscarinic peripheral side effects associated with descarboethoxyloratadine, the main metabolite of loratadine. Br J Pharmacol. 1998, 123: 267P-

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