Author:
Zhang Mengmeng,Liu Hui,Zhu Zhiqiang,Zhang Yu,Zhang Yanyan,Hu Xiaopeng
Abstract
Abstract
Background
Inflammatory myofibroblastic tumor (IMT) is a rare disease that mostly occurs in younger people and is located in the lungs in the general population. We report a rare case of adrenal IMT in a patient with HIV infection, which is believed to be the first of its kind worldwide.
Case presentation
We present a rare case of a 44-year-old man with HIV infection who was diagnosed with adrenal IMT. The patient refused regular highly active antiretroviral therapy 13 years ago until he was admitted to hospital after an adrenal mass was found. The patient underwent successful computed-tomography-guided needle biopsy, and pathological analysis showed fibroblastic–myofibroblastic proliferation with inflammatory infiltration, which confirmed a diagnosis of IMT. We failed to perform complete resection of the tumor because of its diffuse invasion. The patient was complicated with severe multiple pulmonary infections postoperatively because of immunodeficiency, which eventually caused his death 2 months later.
Conclusion
Differential diagnosis of IMT is difficult, and tumor biopsy is an essential means of diagnosis. Surgical resection is preferred for both adrenal and HIV-related IMTs. Conservative treatment should be considered when there are technical difficulties with complete resection, and most patients have achieved good outcomes. However, more cases and longer follow-up are warranted to confirm long-term outcomes of HIV-related IMT.
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Virology,Molecular Medicine
Reference37 articles.
1. Firat O, Ozturk S, Akalin T, Coker A. Inflammatory myofibroblastic tumour. Can J Surg. 2009;52:E60-1.
2. Sim A, Lee MW, Nguyen GK. Inflammatory myofibroblastic tumour of the pancreas. Can J Surg. 2008;51:E23–4.
3. Dalton BG, Thomas PG, Sharp NE, Manalang MA, Fisher JE, Moir CR, et al. Inflammatory myofibroblastic tumors in children. J Pediatr Surg. 2016;51:541–4.
4. Bryl M, Fortuniak J, Wiśniewski K, Bobeff EJ, Jin Y, Papierz W, et al. Inflammatory myofibroblastic tumor of spinal canal: brief case report. J Neurol Surg A Cent Eur Neurosurg. 2020;81:264–70.
5. Zemmoura I, Hamlat A, Morandi X. Intradural extramedullary spinal inflammatory myofibroblastic tumor: case report and literature review. Eur Spine J. 2011;20(Suppl 2):330–5.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献