Diagnosis and Treatment of Keloids and Hypertrophic Scars—Japan Scar Workshop Consensus Document 2018

Author:

Ogawa Rei1,Akita Sadanori2,Akaishi Satoshi3,Aramaki-Hattori Noriko4,Dohi Teruyuki1,Hayashi Toshihiko5,Kishi Kazuo4,Kono Taro6,Matsumura Hajime7,Muneuchi Gan8,Murao Naoki5,Nagao Munetomo9,Okabe Keisuke4,Shimizu Fumiaki10,Tosa Mamiko1,Tosa Yasuyoshi11,Yamawaki Satoko12,Ansai Shinichi13,Inazu Norihisa14,Kamo Toshiko15,Kazki Reiko1,Kuribayashi Shigehiko16

Affiliation:

1. Department of Plastic, Reconstructive and Aesthetic Surgery Nippon Medical School 1-1-5 Sendagi Bunkyo-ku, 113-8603 Tokyo, Japan

2. Department of Plastic Surgery, Wound Repair and Regeneration Fukuoka University, 814-0180 Fukuoka, Japan

3. Department of Plastic Surgery Nippon Medical School Musashikosugi Hospital 1-396 Kosugicho, Nakahara-ku, 211-8533 Kawasaki-shi, Kanagawa, Japan

4. Department of Plastic and Reconstructive Surgery Keio University School of Medicine 35 Shinanomachi, Shinjuku-ku, 160-8582 Tokyo, Japan

5. Department of Plastic and Reconstructive Surgery, Faculty of Medicine and Graduate School of Medicine Hokkaido University Kita-15, Nishi-7, Kita-ku, 060-8638 Sapporo, Japan

6. Department of Plastic Surgery Tokai University School of Medicine 4-1-1 Kitakaname, 259-1292 Hiratsuka, Kanagawa, Japan

7. Department of Plastic and Reconstructive Surgery Tokyo Medical University 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023 Tokyo, Japan

8. Department of Plastic and Reconstructive Surgery Osaka Saiseikai Nakatsu Hospital 2-10-39 Shibata, Kita-ku, 530-0012 Osaka, Japan

9. Department of Plastic, Reconstructive and Aesthetic Surgery Iwate Medical University School of Medicine 19-1 Uchimaru, 020-8505 Morioka, Iwate, Japan

10. Department of Plastic Surgery Oita University Hospital 1-1 Idaigaoka, Hasamamachi, 879-5503 Yufu-shi, Oita, Japan

11. Department of Plastic Surgery Showa University Fujigaoka Hospital 1-30 Fujigaoka, Aoba-ku Yokohama, Kanagawa, Japan

12. Department of Plastic and Reconstructive Surgery Japanese Red Cross Fukui Hospital 2-4-1 Tsukimi, 918-8501 Fukui, Japan

13. Division of Dermatology and Dermatopathology Nippon Medical School Musashikosugi Hospital 1-396, Kosugicho, Nakahara-ku, 211-8533 Kawasaki-shi, Kanagawa, Japan

14. Faculty of Pharmaceutical Sciences Teikyo Heisei University 4-21-2 Nakano, Nakano-ku, 164-8530 Tokyo, Japan

15. Wakamatsu-cho Mental and Skin Clinic 9-4 Wakamatsu-cho, Shinjyuku-ku, 162-0056 Tokyo, Japan

16. Department of Radiation Oncology Nippon Medical School Hospital, 113-8603 Tokyo, Japan

Abstract

Abstract There has been a long-standing need for guidelines on the diagnosis and treatment of keloids and hypertrophic scars that are based on an understanding of the pathomechanisms that underlie these skin fibrotic diseases. This is particularly true for clinicians who deal with Asian and African patients because these ethnicities are highly prone to these diseases. By contrast, Caucasians are less likely to develop keloids and hypertrophic scars, and if they do, the scars tend not to be severe. This ethnic disparity also means that countries vary in terms of their differential diagnostic algorithms. The lack of clear treatment guidelines also means that primary care physicians are currently applying a hotchpotch of treatments, with uneven outcomes. To overcome these issues, the Japan Scar Workshop (JSW) has created a tool that allows clinicians to objectively diagnose and distinguish between keloids, hypertrophic scars, and mature scars. This tool is called the JSW Scar Scale (JSS) and it involves scoring the risk factors of the individual patients and the affected areas. The tool is simple and easy to use. As a result, even physicians who are not accustomed to keloids and hypertrophic scars can easily diagnose them and judge their severity. The JSW has also established a committee that, in cooperation with outside experts in various fields, has prepared a Consensus Document on keloid and hypertrophic scar treatment guidelines. These guidelines are simple and will allow even inexperienced clinicians to choose the most appropriate treatment strategy. The Consensus Document is provided in this article. It describes (1) the diagnostic algorithm for pathological scars and how to differentiate them from clinically similar benign and malignant tumors, (2) the general treatment algorithms for keloids and hypertrophic scars at different medical facilities, (3) the rationale behind each treatment for keloids and hypertrophic scars, and (4) the body site-specific treatment protocols for these scars. We believe that this Consensus Document will be helpful for physicians from all over the world who treat keloids and hypertrophic scars.

Publisher

Oxford University Press (OUP)

Subject

Critical Care and Intensive Care Medicine,Dermatology,Biomedical Engineering,Emergency Medicine,Immunology and Allergy,Surgery

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