Author:
Nazari Elham,Hasanzadeh Malihe,Rezvani Reza,Rejali Marzieh,Badpeyma Mohaddeseh,Delaram Zeinab,Mousavi-Seresht Leila,Akbari Mahdieh,Khazaei Majid,Ferns Gordon A.,Avan Amir
Abstract
Abstract
Introduction
Cervical cancer is one of lethal cancers in women. As a global concern, identifying important factors of cancer is a useful strategy for prevention. Due to the role of diet/nutrition factors for cancer, the purpose of our study was to determine the impact of 150 nutrition/vitamin factors and 50 non-nutritional factor in cervical cancer and phase.
Methods
Population samples of 2088 healthy subjects and patients with cervical cancer were investigated. 200 factors such as vitamin E, B1, B6, fruits, HPV, and age were gathered. Deep learning, Decision tree, and correlation matrix were used for modeling and identifying important factors. SPSS 26, R4.0.3, and Rapid miner were utilized for implementation.
Results
Our findings indicated that zinc, Iron, Niacin, Potassium, Phosphorous, and Cooper have a beneficial impact in reducing the risk of cervical cancer and progression of phase in Iranian women, as well as Salt, snacks and milk Were identified as high-risk food factors (P value < 0.05 and coefficient correlation > 0.6). Also, alcohol, and sex patient with two groups, HPV positive have an impact on cervical cancer incidence. Phosphorus and selenium in the Micronutrients category (R2 = 0.85, AUC = 0.993) and polyunsaturated fatty acid and salt in the Macronutrients category and other categories of nutrients were identified as the most effective factors in cervical cancer using deep learning (R2 = 0.93, AUC = 0.999).
Conclusions
A diet and rich nutrition can be helpful for the prevention of cervix cancer and may reduce the risk of disease. Additional research is necessary for different countries.
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Infectious Diseases,Oncology,Epidemiology
Reference39 articles.
1. Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, et al. Globocan 2012 v1. 0, cancer incidence and mortality worldwide: IARC CancerBase No. 11. Lyon: International Agency for Research On Cancer; 2013. p. 19.
2. Husaiyin S, Han L, Wang L, Ma C, Ainiwaer Z, Rouzi N, Akemujiang M, Simayil H, Aniwa Z, Nurimanguli R, Niyazi M. Factors associated with high-risk HPV infection and cervical cancer screening methods among rural Uyghur women aged > 30 years in Xinjiang. BMC Cancer. 2018;18(1):1–9.
3. Siegel RL, Miller KD, Jemal A. Cancer statics, 2017. CA Cancer J Clin. 2017;67:7–30.
4. Gaffney DK, Hashibe M, Kepka D, Maurer KA, Werner TL. Too many women are dying from cervix cancer: problems and solutions. Gynecol Oncol. 2018;151(3):547–54.
5. Wee LE, Koh GC, Chin RT, Yeo WX, Seow B, Chua D. Socioeconomic factors affecting colorectal, breast and cervical cancer screening in an Asian urban low-income setting at baseline and post-intervention. Prev Med. 2012;55(1):61–7.
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献