Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments-Reference-Cited by-同舟云学术

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Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments

Published:2016-04-01 Issue:1 Volume:4 Page:
ISSN:2049-3002
Container-title:Cancer & Metabolism
language:en
Short-container-title:Cancer Metab

Author:

Peck Barrie,Schug Zachary T.,Zhang Qifeng,Dankworth Beatrice,Jones Dylan T.,Smethurst Elizabeth,Patel Rachana,Mason Susan,Jiang Ming,Saunders Rebecca,Howell Michael,Mitter Richard,Spencer-Dene Bradley,Stamp Gordon,McGarry Lynn,James Daniel,Shanks Emma,Aboagye Eric O.,Critchlow Susan E.,Leung Hing Y.,Harris Adrian L.,Wakelam Michael J. O.,Gottlieb Eyal,Schulze Almut

Funder

Cancer Research UK (GB)

Biotechnology and Biological Sciences Research Council (GB)

Deutsche Krebshilfe

Deutsche Forschungsgemeinschaft

Publisher

Springer Science and Business Media LLC

Subject

General Medicine

Link

http://link.springer.com/content/pdf/10.1186/s40170-016-0146-8.pdf

Reference46 articles.

1. Ward PS, Thompson CB. Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell. 2012;21(3):297–308.

2. Cairns RA, Harris IS, Mak TW. Regulation of cancer cell metabolism. Nat Rev. 2011;11(2):85–95.

3. Lunt SY, Vander Heiden MG. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. Annu Rev Cell Dev Biol. 2011;27:441–64.

4. Denko NC. Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nat Rev. 2008;8(9):705–13.

5. Schulze A, Harris AL. How cancer metabolism is tuned for proliferation and vulnerable to disruption. Nature. 2012;491(7424):364–73.

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