Author:
Sūdžiūtė Kotryna,Murauskienė Greta,Jarienė Kristina,Jaras Algirdas,Minkauskienė Meilė,Adomaitienė Virginija,Nedzelskienė Irena
Abstract
Abstract
Background
This was a hospital registry-based retrospective age-matched cohort study that aimed to compare pregnancy and neonatal outcomes of women with pre-existing mental disorders with those of mentally healthy women.
Methods
A matched cohort retrospective study was carried out in the Department of Obstetrics and Gynecology, Hospital of Lithuanian University of Health Sciences Kauno Klinikos, a tertiary health care institution. Medical records of pregnant women who gave birth from 2006 to 2015 were used. The study group was comprised of 131 pregnant women with mental disorders matched to 228 mentally healthy controls. The primary outcomes assessed were antenatal care characteristics; secondary outcomes were neonatal complications.
Results
Pregnant women with pre-existing mental health disorders were significantly more likely to have low education, be unmarried and unemployed, have a disability that led to lower working capacity, smoke more frequently, have chronic concomitant diseases, attend fewer antenatal visits, gain less weight, be hospitalized during pregnancy, spend more time in hospital during the postpartum period, and were less likely to breastfeed their newborns. The newborns of women with pre-existing mental disorders were small for gestational age (SGA) more often than those of healthy controls (12.9% vs. 7.6%, p < 0.05). No difference was found comparing the methods of delivery.
Conclusions
Women with pre-existing mental health disorders had a worse course of pregnancy. Mental illness increased the risk to deliver a SGA newborn (RR 2.055, 95% CI 1.081–3.908).
Publisher
Springer Science and Business Media LLC
Subject
Obstetrics and Gynecology
Reference28 articles.
1. World Health Organization. Mental Health Determinants and Populations Department of Mental Health and Substance Dependence. Maternal and child mental health program. 2016. http://www.who.int/mental_health/maternal-child/maternal_mental_health/en/.
2. Cannon M, Jones PB, Murray RM. Obstetric complications and schizophrenia: historical and meta-analytic review. Am J Psychiatry. 2002;159(7):1080-92.
3. Hoirisch-Clapauch S, Brenner B, Nardi AE. Adverse obstetric and neonatal outcomes in women with mental disorders. Thromb Res. 2015;135(1):60 – 3.
4. Judd F, Komiti A, Sheehan P, Newman L, Castle D, Everall I. Adverse obstetric and neonatal outcomes in women with severe mental illness: To what extent can they be prevented? Schizophr Res. 2014;157(1–3):305–9.
5. Maghsoudlou S, Cnattingius S, Montgomery S, Aarabi M, Semnani S, Anna-Karin Wikström. et al. Opium use during pregnancy and infant size at birth: a cohort study. BMC Pregnancy and Childbirth. 2018;18(1)358.
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