Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation

Author:

Kim Kyungpil,Bolotin Eugene,Theusch Elizabeth,Huang Haiyan,Medina Marisa W,Krauss Ronald M

Publisher

Springer Science and Business Media LLC

Reference39 articles.

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2. Simon JA, Lin F, Hulley SB, Blanche PJ, Waters D, Shiboski S, Rotter JI, Nickerson DA, Yang H, Saad M, Krauss RM: Phenotypic predictors of response to simvastatin therapy among african-americans and caucasians: The Cholesterol and Pharmacogenetics (CAP) study. Am J Cardiol. 2006, 97: 843-850. 10.1016/j.amjcard.2005.09.134.

3. Ridker PM, Danielson E, Fonseca FAH, Genest J, Gotto AM, Kastelein JJP, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ: Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med. 2008, 359: 2195-2207. 10.1056/NEJMoa0807646.

4. Barber MJ, Mangravite LM, Hyde CL, Chasman DI, Smith JD, McCarty CA, Li X, Wilke RA, Rieder MJ, Williams PT, Ridker PM, Chatterjee A, Rotter JI, Nickerson DA, Stephens M, Krauss RM: Genome-wide association of lipid-lowering response to statins in combined study populations. PLoS One. 2010, 5: e9763-10.1371/journal.pone.0009763.

5. Krauss RM, Mangravite LM, Smith JD, Medina MW, Wang D, Guo X, Rieder MJ, Simon JA, Hulley SB, Waters D, Saad M, Williams PT, Taylor KD, Yang H, Nickerson DA, Rotter JI: Variation in the 3-hydroxyl-3-methylglutaryl coenzyme A reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment. Circulation. 2008, 117: 1537-1544. 10.1161/CIRCULATIONAHA.107.708388.

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