Author:
Nieman Gary,Kollisch-Singule Michaela,Ramcharran Harry,Satalin Joshua,Blair Sarah,Gatto Louis A.,Andrews Penny,Ghosh Auyon,Kaczka David W.,Gaver Donald,Bates Jason,Habashi Nader M.
Abstract
AbstractA hallmark of ARDS is progressive shrinking of the ‘baby lung,’ now referred to as the ventilator-induced lung injury (VILI) ‘vortex.’ Reducing the risk of the VILI vortex is the goal of current ventilation strategies; unfortunately, this goal has not been achieved nor has mortality been reduced. However, the temporal aspects of a mechanical breath have not been considered. A brief expiration prevents alveolar collapse, and an extended inspiration can recruit the atelectatic lung over hours. Time-controlled adaptive ventilation (TCAV) is a novel ventilator approach to achieve these goals, since it considers many of the temporal aspects of dynamic lung mechanics.
Funder
National Heart, Lung, and Blood Institute
Congressionally Directed Medical Research Programs
Publisher
Springer Science and Business Media LLC
Subject
Critical Care and Intensive Care Medicine
Cited by
8 articles.
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