Author:
Villar Jesús,Szakmany Tamas,Grasselli Giacomo,Camporota Luigi
Abstract
AbstractAlthough the defining elements of “acute respiratory distress syndrome” (ARDS) have been known for over a century, the syndrome was first described in 1967. Since then, despite several revisions of its conceptual definition, it remains a matter of debate whether ARDS is a discrete nosological entity. After almost 60 years, it is appropriate to examine how critical care has modeled this fascinating syndrome and affected patient’s outcome. Given that the diagnostic criteria of ARDS (e.g., increased pulmonary vascular permeability and diffuse alveolar damage) are difficult to ascertain in clinical practice, we believe that a step forward would be to standardize the assessment of pulmonary and extrapulmonary involvement in ARDS to ensure that each patient can receive the most appropriate and effective treatment. The selection of treatments based on arbitrary ranges of PaO2/FiO2 lacks sufficient sensitivity to individualize patient care.
Funder
Instituto de Salud Carlos III
ERAPerMed
The European Reginal Development's Funds
Fundación Canaria Instituto de Investigación Sanitaria de Canarias
Asociación Científica Pulmón y Ventilación Mecánica, Spain
Ministero della Salute
Publisher
Springer Science and Business Media LLC
Subject
Critical Care and Intensive Care Medicine
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