Auditory cognitive assessment in post COVID-19 patients: a case control study
-
Published:2024-01-09
Issue:1
Volume:40
Page:
-
ISSN:2090-8539
-
Container-title:The Egyptian Journal of Otolaryngology
-
language:en
-
Short-container-title:Egypt J Otolaryngol
Author:
Weheiba Hoda Mahmoud, Kabarity Rasha Hamdi E. L., Shaheen Heba MagdyORCID, EL-Gendy Abeer Mohamed Mohamed
Abstract
Abstract
Background
There is increasing evidence suggesting that individuals with coronavirus disease 2019 (COVID-19) may experience symptoms that persist beyond the initial acute phase commonly referred to as “Long COVID.” Cognitive deficits were among the frequently reported long-lasting symptoms post-COVID-19. Consequently, the study was designed to evaluate cognitive-communicative abilities in post COVID-19 patients focusing on auditory memory and auditory attention and to study the effect of different variables on these abilities in post COVID-19 patients.
Methods
Eighty adult subjects were divided equally according to the presence or absence of a history of COVID-19 infection into the study and control group, respectively. All subjects were submitted to thorough history taking, basic audiological evaluation, auditory cognitive psychophysical tests including Auditory Continuous Performance test, Speech Intelligibility in Noise, Recognition memory, Memory for content and for sequence tests, digit span forward and backward tests, and electrophysiological auditory event-related potential (P300).
Results
Post COVID-19 group showed significantly lower scores compared to the control group in all psychophysical auditory cognitive tests for attention and memory and significantly prolonged P300 wave latency and smaller amplitude. None of the variables measured (including duration passed from infection, severity, and number of infection) showed significant relations to test results except a significant negative correlation between the number of infections and memory for sequence results.
Conclusion
Single infection with COVID-19 can have a prolonged impact on auditory cognitive abilities which were not related to the degree of severity of COVID-19. Thus, patients recovered from COVID-19 should receive auditory cognitive evaluations to detect even mild cognitive deficits that can affect quality of life.
Publisher
Springer Science and Business Media LLC
Subject
Otorhinolaryngology
Reference33 articles.
1. Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, Kang L, Guo L, Liu M, Zhou X, Luo J, Huang Z, Tu S, Zhao Y, Chen L, Xu D, Li Y, Li C, Peng L, Li Y, Xie W, Cui D, Shang L, Fan G, Xu J, Wang G, Wang Y, Zhong J, Wang C, Wang J, Zhang D, Cao B (2021) 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet 397(10270):220–232. https://doi.org/10.1016/S0140-6736(20)32656-8. Epub 2021 Jan 8. PMID: 33428867; PMCID: PMC7833295 2. Ellul MA, Benjamin L, Singh B, Lant S, Michael BD, Easton A, Kneen R, Defres S, Sejvar J, Solomon T (2020) Neurological associations of COVID-19. Lancet Neurol 19(9):767–783. https://doi.org/10.1016/S1474-4422(20)30221-0. Epub 2020 Jul 2. PMID: 32622375; PMCID: PMC7332267 3. Varatharaj A, Thomas N, Ellul MA, Davies NWS, Pollak TA, Tenorio EL, Sultan M, Easton A, Breen G, Zandi M, Coles JP, Manji H, Al-Shahi Salman R, Menon DK, Nicholson TR, Benjamin LA, Carson A, Smith C, Turner MR, Solomon T, Kneen R, Pett SL, Galea I, Thomas RH, Michael BD, CoroNerve Study Group (2020) Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study. Lancet Psychiatry 7(10):875–882. https://doi.org/10.1016/S2215-0366(20)30287-X. Epub 2020 Jun 25. Erratum in: Lancet Psychiatry. 2020 Jul 14;: PMID: 32593341; PMCID: PMC7316461 4. Tenforde MW, Kim SS, Lindsell CJ, Billig Rose E, Shapiro NI, Files DC, Gibbs KW, Erickson HL, Steingrub JS, Smithline HA, Gong MN, Aboodi MS, Exline MC, Henning DJ, Wilson JG, Khan A, Qadir N, Brown SM, Peltan ID, Rice TW, Hager DN, Ginde AA, Stubblefield WB, Patel MM, Self WH, Feldstein LR, IVY Network Investigators, CDC COVID-19 Response Team, IVY Network Investigators (2020) Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a Multistate Health Care Systems Network-United States, March-June 2020. MMWR Morb Mortal Wkly Rep 69(30):993–998. https://doi.org/10.15585/mmwr.mm6930e1. PMID: 32730238; PMCID: PMC7392393 5. Chen C, Haupert SR, Zimmermann L, Shi X, Fritsche LG, Mukherjee B (2022) Global Prevalence of Post-Coronavirus Disease 2019 (COVID-19) Condition or long COVID: a meta-analysis and systematic review. J Infect Dis 226(9):1593–1607. https://doi.org/10.1093/infdis/jiac136. PMID:35429399;PMCID:PMC9047189
|
|