Abstract
Abstract
Background
Schizophrenia is associated with widespread cognitive impairment. The MATRICS Consensus Cognitive Battery (MCCB) is most frequently used to assess cognitive function. However, the MCCB test is time consuming for the clinician. Virtual reality (VR) has emerged as an adjunctive tool to overcome this limitation and provides a new means to assess cognitive function.
Methods
The present study examined the validity and safety of using VR technology to assess cognitive function in Han Chinese patients with schizophrenia (SZs). The VR cognition training system (VRCTS) was used to simulate real-life supermarkets and assess cognitive function. Thirty-two SZs and 25 healthy controls (HCs) underwent VRCTS and MCCB assessments. An auxiliary diagnosis model was created based on the outcomes of the VRCTS to classify SZs and HCs by cognitive impairment.
Results
Significant differences in completion time between the SZs and HCs were detected using the VRCTS. SZs spent more time completing tasks than HCs. The outcome of VRCTS significantly correlated with the MCCB. The auxiliary diagnosis model had a sensitivity of 88.89% and a specificity of 88.89%.
Conclusions
These results support the use of VR technology in the assessment of cognitive impairment in Han Chinese schizophrenia patients.
Trial registration
China Clinical Trial Registry, ChiVTR1800016121. Registered 13 May 2018, http://www.chictr.org.cn/showproj.aspx?proj=27233
Funder
National Key Research and Development Program of China
Basic Public Welfare Research projects in Zhejiang Province
Major Subject of Zhejiang Province
Zhejiang Provincial Science and Technology Department
Publisher
Springer Science and Business Media LLC
Subject
Psychiatry and Mental health
Cited by
6 articles.
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