Spiroquinazolinone-induced cytotoxicity and apoptosis in K562 human leukemia cells: alteration in expression levels of Bcl-2 and Bax
Author:
Affiliation:
1. Department of Biology, Faculty of Natural Science, University of Tabriz, Iran
2. Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Iran
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/40/1/40_115/_pdf
Reference41 articles.
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2. Adams, J.M. and Cory, S. (1998): The Bcl-2 protein family: arbiters of cell survival. Science, 281, 1322-1326.
3. Adams, J.M. and Cory, S. (2007): Bcl-2-regulated apoptosis: mechanism and therapeutic potential. Curr. Opin. Immunol., 19, 488-496.
4. Billen, L., Shamas-Din, A. and Andrews, D. (2008): Bid: a Bax-like BH3 protein. Oncogene, 27, S93-S104.
5. Boersma, A.W., Nooter, K., Burger, H., Kortland, C.J. and Stoter, G. (1997): Bax upregulation is an early event in cisplatin-induced apoptosis in human testicular germ-cell tumor cell line NT2, as quantitated by flow cytometry. Cytometry, 27, 275-282.
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