Pharmacogenomics of CYP2D6: Molecular Genetics, Interethnic Differences and Clinical Importance

Author:

Teh Lay Kek,Bertilsson Leif

Publisher

Japanese Society for the Study of Xenobiotics

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference160 articles.

1. Molecular basis of polymorphic drug metabolism;Daly;J. Mol. Med.,1995

2. “It's the genes, stupid”. Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism;Kroemer;Life Sci.,1995

3. Pharmacogenetics: a laboratory tool for optimizing therapeutic efficiency;Linder;Clin. Chem.,1997

4. Role of environmental factors in the pharmacokinetics of drugs: Considerations with respect to animal models, P-450 enzymes, and probe drugs;Pelkonen;Handb. Exp. Pharmacol.,1994

5. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians;Shimada;J. Pharmacol. Exp. Ther.,1994

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