Small Cell Lung Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology

Author:

Ganti Apar Kishor P.1,Loo Billy W.2,Bassetti Michael3,Blakely Collin4,Chiang Anne5,D'Amico Thomas A.6,D'Avella Christopher7,Dowlati Afshin8,Downey Robert J.9,Edelman Martin10,Florsheim Charles11,Gold Kathryn A.12,Goldman Jonathan W.13,Grecula John C.14,Hann Christine15,Iams Wade16,Iyengar Puneeth17,Kelly Karen18,Khalil Maya19,Koczywas Marianna20,Merritt Robert E.14,Mohindra Nisha21,Molina Julian22,Moran Cesar23,Pokharel Saraswati24,Puri Sonam25,Qin Angel26,Rusthoven Chad27,Sands Jacob28,Santana-Davila Rafael29,Shafique Michael30,Waqar Saiama N.31,Gregory Kristina M.32,Hughes Miranda32

Affiliation:

1. 1Fred & Pamela Buffett Cancer Center;

2. 2Stanford Cancer Institute;

3. 3University of Wisconsin Carbone Cancer Center;

4. 4UCSF Helen Diller Family Comprehensive Cancer Center;

5. 5Yale Cancer Center/Smilow Cancer Hospital;

6. 6Duke Cancer Institute;

7. 7Abramson Cancer Center at the University of Pennsylvania;

8. 8Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;

9. 9Memorial Sloan Kettering Cancer Center;

10. 10Fox Chase Cancer Center;

11. 11Patient Advocate;

12. 12UC San Diego Moores Cancer Center;

13. 13UCLA Jonsson Comprehensive Cancer Center;

14. 14The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;

15. 15The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;

16. 16Vanderbilt-Ingram Cancer Center;

17. 17UT Southwestern Simmons Comprehensive Cancer Center;

18. 18UC Davis Comprehensive Cancer Center;

19. 19O'Neal Comprehensive Cancer Center at UAB;

20. 20City of Hope National Medical Center;

21. 21Robert H. Lurie Comprehensive Cancer Center of Northwestern University;

22. 22Mayo Clinic Cancer Center;

23. 23The University of Texas MD Anderson Cancer Center;

24. 24Roswell Park Comprehensive Cancer Center;

25. 25Huntsman Cancer Institute at the University of Utah;

26. 26University of Michigan Rogel Cancer Center;

27. 27University of Colorado Cancer Center;

28. 28Dana Farber/Brigham and Women's Cancer Center;

29. 29Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;

30. 30Moffitt Cancer Center;

31. 31Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;

32. 32National Comprehensive Cancer Network.

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Small Cell Lung Cancer (SCLC) provide recommended management for patients with SCLC, including diagnosis, primary treatment, surveillance for relapse, and subsequent treatment. This selection for the journal focuses on metastatic (known as extensive-stage) SCLC, which is more common than limited-stage SCLC. Systemic therapy alone can palliate symptoms and prolong survival in most patients with extensive-stage disease. Smoking cessation counseling and intervention should be strongly promoted in patients with SCLC and other high-grade neuroendocrine carcinomas. The “Summary of the Guidelines Updates” section in the SCLC algorithm outlines the most recent revisions for the 2022 update, which are described in greater detail in this revised Discussion text.

Publisher

Harborside Press, LLC

Subject

Oncology

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