Pediatric Acute Lymphoblastic Leukemia, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology-Reference-Cited by-同舟云学术

Pediatric Acute Lymphoblastic Leukemia, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology

Published:2020-01 Issue:1 Volume:18 Page:81-112
ISSN:1540-1405
Container-title:Journal of the National Comprehensive Cancer Network
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Author:

Brown Patrick¹,Inaba Hiroto²,Annesley Colleen³,Beck Jill⁴,Colace Susan⁵,Dallas Mari⁶,DeSantes Kenneth⁷,Kelly Kara⁸,Kitko Carrie⁹,Lacayo Norman¹⁰,Larrier Nicole¹¹,Maese Luke¹²,Mahadeo Kris¹³,Nanda Ronica¹⁴,Nardi Valentina¹⁵,Rodriguez Vilmarie¹⁶,Rossoff Jenna¹⁷,Schuettpelz Laura¹⁸,Silverman Lewis¹⁹,Sun Jessica¹¹,Sun Weili²⁰,Teachey David²¹,Wong Victor²²,Yanik Gregory²³,Johnson-Chilla Alyse²⁴,Ogba Ndiya²⁴

Affiliation:

1. 1The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;

2. 2St. Jude Children's Research Hospital/The University of Tennessee Health Science Center;

3. 3Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;

4. 4Fred & Pamela Buffett Cancer Center;

5. 5The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;

6. 6Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;

7. 7University of Wisconsin Carbone Cancer Center;

8. 8Roswell Park Comprehensive Cancer Center;

9. 9Vanderbilt-Ingram Cancer Center;

10. 10Stanford Cancer Institute;

11. 11Duke Cancer Institute;

12. 12Huntsman Cancer Institute at the University of Utah;

13. 13The University of Texas MD Anderson Cancer Center;

14. 14Moffitt Cancer Center;

15. 15Massachusetts General Hospital Cancer Center;

16. 16Mayo Clinic Cancer Center;

17. 17Ann & Robert H. Lurie Children’s Hospital of Chicago;

18. 18Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;

19. 19Dana-Farber/Brigham and Women's Cancer Center;

20. 20City of Hope National Medical Center;

21. 21Abramson Cancer Center at the University of Pennsylvania;

22. 22UC San Diego Moores Cancer Center;

23. 23University of Michigan Rogel Cancer Center; and

24. 24National Comprehensive Cancer Network.

Abstract

Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. Advancements in technology that enhance our understanding of the biology of the disease, risk-adapted therapy, and enhanced supportive care have contributed to improved survival rates. However, additional clinical management is needed to improve outcomes for patients classified as high risk at presentation (eg, T-ALL, infant ALL) and who experience relapse. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for pediatric ALL provide recommendations on the workup, diagnostic evaluation, and treatment of the disease, including guidance on supportive care, hematopoietic stem cell transplantation, and pharmacogenomics. This portion of the NCCN Guidelines focuses on the frontline and relapsed/refractory management of pediatric ALL.

Publisher

Harborside Press, LLC

Subject

Oncology

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