NCCN Guidelines® Insights: Breast Cancer, Version 4.2023

Author:

Gradishar William J.1,Moran Meena S.2,Abraham Jame3,Abramson Vandana4,Aft Rebecca5,Agnese Doreen6,Allison Kimberly H.7,Anderson Bethany8,Burstein Harold J.9,Chew Helen10,Dang Chau11,Elias Anthony D.12,Giordano Sharon H.13,Goetz Matthew P.14,Goldstein Lori J.15,Hurvitz Sara A.16,Jankowitz Rachel C.17,Javid Sara H.18,Krishnamurthy Jairam19,Leitch A. Marilyn20,Lyons Janice3,Mortimer Joanne21,Patel Sameer A.15,Pierce Lori J.22,Rosenberger Laura H.23,Rugo Hope S.24,Schneider Bryan25,Smith Mary Lou26,Soliman Hatem27,Stringer-Reasor Erica M.28,Telli Melinda L.7,Wei Mei29,Wisinski Kari B.8,Young Jessica S.30,Yeung Kay31,Dwyer Mary A.32,Kumar Rashmi32

Affiliation:

1. Robert H. Lurie Comprehensive Cancer Center of Northwestern University

2. Yale Cancer Center/Smilow Cancer Hospital

3. Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute

4. Vanderbilt-Ingram Cancer Center

5. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine

6. The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute

7. Stanford Cancer Institute

8. University of Wisconsin Carbone Cancer Center

9. Dana-Farber/Brigham and Women’s Cancer Center

10. UC Davis Comprehensive Cancer Center

11. Memorial Sloan Kettering Cancer Center

12. University of Colorado Cancer Center

13. The University of Texas MD Anderson Cancer Center

14. Mayo Clinic Comprehensive Cancer Center

15. Fox Chase Cancer Center

16. UCLA Jonsson Comprehensive Cancer Center

17. Abramson Cancer Center at the University of Pennsylvania

18. Fred Hutchinson Cancer Center

19. Fred & Pamela Buffet Cancer Center

20. UT Southwestern Simmons Comprehensive Cancer Center

21. City of Hope National Medical Center

22. University of Michigan Rogel Cancer Center

23. Duke Cancer Institute

24. UCSF Helen Diller Family Comprehensive Cancer Center

25. Indiana University Melvin and Bren Simon Comprehensive Cancer Center

26. Research Advocacy Network

27. Moffitt Cancer Center

28. O’Neal Comprehensive Cancer Center at UAB

29. Huntsman Cancer Institute at the University of Utah

30. Roswell Park Comprehensive Cancer Center

31. UC San Diego Moores Cancer Center

32. National Comprehensive Cancer Network

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer address all aspects of management for breast cancer. The treatment landscape of metastatic breast cancer is evolving constantly. The therapeutic strategy takes into consideration tumor biology, biomarkers, and other clinical factors. Due to the growing number of treatment options, if one option fails, there is usually another line of therapy available, providing meaningful improvements in survival. This NCCN Guidelines Insights report focuses on recent updates specific to systemic therapy recommendations for patients with stage IV (M1) disease.

Publisher

Harborside Press, LLC

Subject

Oncology

Reference56 articles.

1. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Sung H,2021

2. Cancer statistics, 2023;Siegel RL,2023

3. Change in survival in metastatic breast cancer with treatment advances: meta-analysis and systematic review;Caswell-Jin JL,2018

4. 5th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 5);Cardoso F,2020

5. Palbociclib and letrozole in advanced breast cancer;Finn RS,2016

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