NCCN Guidelines® Insights: Melanoma: Cutaneous, Version 2.2021

Author:

Swetter Susan M.1,Thompson John A.2,Albertini Mark R.3,Barker Christopher A.4,Baumgartner Joel5,Boland Genevieve6,Chmielowski Bartosz7,DiMaio Dominick8,Durham Alison9,Fields Ryan C.10,Fleming Martin D.11,Galan Anjela12,Gastman Brian13,Grossmann Kenneth14,Guild Samantha15,Holder Ashley16,Johnson Douglas17,Joseph Richard W.18,Karakousis Giorgos19,Kendra Kari20,Lange Julie R.21,Lanning Ryan22,Margolin Kim23,Olszanski Anthony J.24,Ott Patrick A.25,Ross Merrick I.26,Salama April K.27,Sharma Rohit28,Skitzki Joseph29,Sosman Jeffrey30,Wuthrick Evan31,McMillian Nicole R.32,Engh Anita M.32

Affiliation:

1. 1Stanford Cancer Institute;

2. 2Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;

3. 3University of Wisconsin Carbone Cancer Center;

4. 4Memorial Sloan Kettering Cancer Center;

5. 5UC San Diego Moores Cancer Center;

6. 6Massachusetts General Hospital Cancer Center;

7. 7UCLA Jonsson Comprehensive Cancer Center;

8. 8Fred & Pamela Buffett Cancer Center;

9. 9University of Michigan Rogel Cancer Center;

10. 10Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;

11. 11St. Jude Children’s Research Hospital/The University of Tennessee Health Science Center;

12. 12Yale Cancer Center/Smilow Cancer Hospital;

13. 13Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;

14. 14Huntsman Cancer Institute at the University of Utah;

15. 15AIM at Melanoma;

16. 16O'Neal Comprehensive Cancer Center at UAB;

17. 17Vanderbilt-Ingram Cancer Center;

18. 18Mayo Clinic Cancer Center;

19. 19Abramson Cancer Center at the University of Pennsylvania;

20. 20The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;

21. 21The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;

22. 22University of Colorado Cancer Center;

23. 23City of Hope National Medical Center;

24. 24Fox Chase Cancer Center;

25. 25Dana-Farber/Brigham and Women's Cancer Center;

26. 26The University of Texas MD Anderson Cancer Center;

27. 27Duke Cancer Institute;

28. 28UT Southwestern Simmons Comprehensive Cancer Center;

29. 29Roswell Park Comprehensive Cancer Center;

30. 30Robert H. Lurie Comprehensive Cancer Center of Northwestern University;

31. 31Moffitt Cancer Center; and

32. 32National Comprehensive Cancer Network.

Abstract

Over the past few years, the NCCN Guidelines for Melanoma: Cutaneous have been expanded to include pathways for treatment of microscopic satellitosis (added in v2.2020), and the following Principles sections: Molecular Testing (added in v2.2019), Systemic Therapy Considerations (added in v2.2020), and Brain Metastases Management (added in v3.2020). The v1.2021 update included additional modifications of these sections and notable revisions to Principles of: Pathology, Surgical Margins for Wide Excision of Primary Melanoma, Sentinel Lymph Node Biopsy, Completion/Therapeutic Lymph Node Dissection, and Radiation Therapy. These NCCN Guidelines Insights discuss the important changes to pathology and surgery recommendations, as well as additions to systemic therapy options for patients with advanced disease.

Publisher

Harborside Press, LLC

Subject

Oncology

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