Chronic Myeloid Leukemia, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology

Author:

Deininger Michael W.1,Shah Neil P.2,Altman Jessica K.3,Berman Ellin4,Bhatia Ravi5,Bhatnagar Bhavana6,DeAngelo Daniel J.7,Gotlib Jason8,Hobbs Gabriela9,Maness Lori10,Mead Monica11,Metheny Leland12,Mohan Sanjay13,Moore Joseph O.14,Naqvi Kiran15,Oehler Vivian16,Pallera Arnel M.17,Patnaik Mrinal18,Pratz Keith19,Pusic Iskra20,Rose Michal G.21,Smith B. Douglas22,Snyder David S.23,Sweet Kendra L.24,Talpaz Moshe25,Thompson James26,Yang David T.27,Gregory Kristina M.28,Sundar Hema28

Affiliation:

1. 1Huntsman Cancer Institute at the University of Utah;

2. 2UCSF Helen Diller Family Comprehensive Cancer Center;

3. 3Robert H. Lurie Comprehensive Cancer Center of Northwestern University;

4. 4Memorial Sloan Kettering Cancer Center;

5. 5O'Neal Comprehensive Cancer Center at UAB;

6. 6The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;

7. 7Dana-Farber/Brigham and Women’s Cancer Center;

8. 8Stanford Cancer Institute;

9. 9Massachusetts General Hospital Cancer Center;

10. 10Fred and Pamela Buffett Cancer Center;

11. 11UCLA Jonsson Comprehensive Cancer Center;

12. 12Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;

13. 13Vanderbilt-Ingram Cancer Center;

14. 14Duke Cancer Institute;

15. 15The University of Texas MD Anderson Cancer Center;

16. 16Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;

17. 17St. Jude Children's Research Hospital/The University of Tennessee Health Science Center;

18. 18Mayo Clinic Cancer Center;

19. 19Abramson Cancer Center at the University of Pennsylvania;

20. 20Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;

21. 21Yale Cancer Center/Smilow Cancer Hospital;

22. 22The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;

23. 23City of Hope National Medical Center;

24. 24Moffitt Cancer Center;

25. 25University of Michigan Rogel Cancer Center;

26. 26Roswell Park Comprehensive Cancer Center;

27. 27University of Wisconsin Carbone Cancer Center; and

28. 28National Comprehensive Cancer Network

Abstract

Chronic myeloid leukemia (CML) is defined by the presence of Philadelphia chromosome (Ph) which results from a reciprocal translocation between chromosomes 9 and 22 [t(9;22] that gives rise to aBCR-ABL1fusion gene. CML occurs in 3 different phases (chronic, accelerated, and blast phase) and is usually diagnosed in the chronic phase. Tyrosine kinase inhibitor therapy is a highly effective first-line treatment option for all patients with newly diagnosed chronic phase CML. This manuscript discusses the recommendations outlined in the NCCN Guidelines for the diagnosis and management of patients with chronic phase CML.

Publisher

Harborside Press, LLC

Subject

Oncology

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3