Acute Myeloid Leukemia, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology

Author:

Tallman Martin S.1,Wang Eunice S.2,Altman Jessica K.3,Appelbaum Frederick R.4,Bhatt Vijaya Raj5,Bixby Dale6,Coutre Steven E.7,De Lima Marcos8,Fathi Amir T.9,Fiorella Melanie10,Foran James M.11,Hall Aric C.12,Jacoby Meagan13,Lancet Jeffrey14,LeBlanc Thomas W.15,Mannis Gabriel7,Marcucci Guido16,Martin Michael G.17,Mims Alice18,O’Donnell Margaret R.16,Olin Rebecca19,Peker Deniz20,Perl Alexander21,Pollyea Daniel A.22,Pratz Keith23,Prebet Thomas24,Ravandi Farhad25,Shami Paul J.26,Stone Richard M.27,Strickland Stephen A.28,Wieduwilt Matthew10,Gregory Kristina M.,Hammond Lydia29,Ogba Ndiya29,

Affiliation:

1. 1Memorial Sloan Kettering Cancer Center;

2. 2Roswell Park Comprehensive Cancer Center;

3. 3Robert H. Lurie Comprehensive Cancer Center of Northwestern University;

4. 4Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;

5. 5Fred & Pamela Buffett Cancer Center;

6. 6University of Michigan Rogel Cancer Center;

7. 7Stanford Cancer Institute;

8. 8Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;

9. 9Massachusetts General Hospital Cancer Center;

10. 10UC San Diego Moores Cancer Center;

11. 11Mayo Clinic Cancer Center;

12. 12University of Wisconsin Carbone Cancer Center;

13. 13Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;

14. 14Moffitt Cancer Center;

15. 15Duke Cancer Institute;

16. 16City of Hope National Medical Center;

17. 17St. Jude Children’s Research Hospital/The University of Tennessee Health Science Center;

18. 18The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;

19. 19UCSF Helen Diller Family Comprehensive Cancer Center;

20. 20O’Neal Comprehensive Cancer Center at UAB;

21. 21Abramson Cancer Center at the University of Pennsylvania;

22. 22University of Colorado Cancer Center;

23. 23The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;

24. 24Yale Cancer Center/Smilow Cancer Hospital;

25. 25The University of Texas MD Anderson Cancer Center;

26. 26Huntsman Cancer Institute at the University of Utah;

27. 27Dana-Farber/Brigham and Women’s Cancer Center;

28. 28Vanderbilt-Ingram Cancer Center; and

29. 29National Comprehensive Cancer Network

Abstract

Acute myeloid leukemia (AML) is the most common form of acute leukemia among adults and accounts for the largest number of annual deaths due to leukemias in the United States. Recent advances have resulted in an expansion of treatment options for AML, especially concerning targeted therapies and low-intensity regimens. This portion of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for AML focuses on the management of AML and provides recommendations on the workup, diagnostic evaluation and treatment options for younger (age <60 years) and older (age ≥60 years) adult patients.

Publisher

Harborside Press, LLC

Subject

Oncology

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