NCCN Guidelines® Insights: Head and Neck Cancers, Version 1.2022

Author:

Caudell Jimmy J.1,Gillison Maura L.2,Maghami Ellie3,Spencer Sharon4,Pfister David G.5,Adkins Douglas6,Birkeland Andrew C.7,Brizel David M.8,Busse Paul M.9,Cmelak Anthony J.10,Colevas A. Dimitrios11,Eisele David W.12,Galloway Thomas13,Geiger Jessica L.14,Haddad Robert I.15,Hicks Wesley L.16,Hitchcock Ying J.17,Jimeno Antonio18,Leizman Debra14,Mell Loren K.19,Mittal Bharat B.20,Pinto Harlan A.11,Rocco James W.21,Rodriguez Cristina P.22,Savvides Panayiotis S.23,Schwartz David24,Shah Jatin P.5,Sher David25,St. John Maie26,Weber Randal S.2,Weinstein Gregory27,Worden Frank28,Yang Bruce Justine29,Yom Sue S.30,Zhen Weining31,Burns Jennifer L.32,Darlow Susan D.32

Affiliation:

1. 1Moffitt Cancer Center;

2. 2The University of Texas MD Anderson Cancer Center;

3. 3City of Hope National Medical Center;

4. 4O'Neal Comprehensive Cancer Center at UAB;

5. 5Memorial Sloan Kettering Cancer Center;

6. 6Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;

7. 7UC Davis Comprehensive Cancer Center;

8. 8Duke Cancer Institute;

9. 9Massachusetts General Hospital Cancer Center;

10. 10Vanderbilt-Ingram Cancer Center;

11. 11Stanford Cancer Institute;

12. 12The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;

13. 13Fox Chase Cancer Center;

14. 14Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;

15. 15Dana-Farber/Brigham and Women’s Cancer Center;

16. 16Roswell Park Comprehensive Cancer Center;

17. 17Huntsman Cancer Institute at the University of Utah;

18. 18University of Colorado Cancer Center;

19. 19UC San Diego Moores Cancer Center;

20. 20Robert H. Lurie Comprehensive Cancer Center of Northwestern University;

21. 21The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute;

22. 22Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;

23. 23Mayo Clinic Cancer Center;

24. 24St. Jude Children’s Research Hospital/The University of Tennessee Health Science Center;

25. 25UT Southwestern Simmons Comprehensive Cancer Center;

26. 26UCLA Jonsson Comprehensive Cancer Center;

27. 27Abramson Cancer Center at the University of Pennsylvania;

28. 28University of Michigan Rogel Cancer Center;

29. 29University of Wisconsin Carbone Cancer Center;

30. 30UCSF Helen Diller Family Comprehensive Cancer Center;

31. 31Fred & Pamela Buffett Cancer Center; and

32. 32National Comprehensive Cancer Network.

Abstract

The NCCN Guidelines for Head and Neck Cancers address tumors arising in the oral cavity (including mucosal lip), pharynx, larynx, and paranasal sinuses. Occult primary cancer, salivary gland cancer, and mucosal melanoma (MM) are also addressed. The specific site of disease, stage, and pathologic findings guide treatment (eg, the appropriate surgical procedure, radiation targets, dose and fractionation of radiation, indications for systemic therapy). The NCCN Head and Neck Cancers Panel meets at least annually to review comments from reviewers within their institutions, examine relevant new data from publications and abstracts, and reevaluate and update their recommendations. These NCCN Guidelines Insights summarize the panel’s most recent recommendations regarding management of HPV-positive oropharynx cancer and ongoing research in this area.

Publisher

Harborside Press, LLC

Subject

Oncology

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