Central Nervous System Cancers, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology

Author:

Nabors Louis Burt1,Portnow Jana2,Ahluwalia Manmeet3,Baehring Joachim4,Brem Henry5,Brem Steven6,Butowski Nicholas7,Campian Jian L.8,Clark Stephen W.9,Fabiano Andrew J.10,Forsyth Peter11,Hattangadi-Gluth Jona12,Holdhoff Matthias5,Horbinski Craig13,Junck Larry14,Kaley Thomas15,Kumthekar Priya13,Loeffler Jay S.16,Mrugala Maciej M.17,Nagpal Seema18,Pandey Manjari19,Parney Ian17,Peters Katherine20,Puduvalli Vinay K.21,Robins Ian22,Rockhill Jason23,Rusthoven Chad24,Shonka Nicole25,Shrieve Dennis C.26,Swinnen Lode J.5,Weiss Stephanie27,Wen Patrick Yung28,Willmarth Nicole E.29,Bergman Mary Anne30,Darlow Susan D.30

Affiliation:

1. 1O'Neal Comprehensive Cancer Center at UAB;

2. 2City of Hope National Medical Center;

3. 3Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;

4. 4Yale Cancer Center/Smilow Cancer Hospital;

5. 5The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;

6. 6Abramson Cancer Center at the University of Pennsylvania;

7. 7UCSF Helen Diller Family Comprehensive Cancer Center;

8. 8Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;

9. 9Vanderbilt-Ingram Cancer Center;

10. 10Roswell Park Comprehensive Cancer Center;

11. 11Moffitt Cancer Center;

12. 12UC San Diego Moores Cancer Center;

13. 13Robert H. Lurie Comprehensive Cancer Center of Northwestern University;

14. 14University of Michigan Rogel Cancer Center;

15. 15Memorial Sloan Kettering Cancer Center;

16. 16Massachusetts General Hospital Cancer Center;

17. 17Mayo Clinic Cancer Center;

18. 18Stanford Cancer Institute;

19. 19St. Jude Children's Research Hospital/The University of Tennessee Health Science Center;

20. 20Duke Cancer Institute;

21. 21The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;

22. 22University of Wisconsin Carbone Cancer Center;

23. 23Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;

24. 24University of Colorado Cancer Center;

25. 25Fred and Pamela Buffet Cancer Center;

26. 26Huntsman Cancer Institute at the University of Utah;

27. 27Fox Chase Cancer Center;

28. 28Dana-Farber Cancer Institute;

29. 29American Brain Tumor Association; and

30. 30National Comprehensive Cancer Network

Abstract

The NCCN Guidelines for Central Nervous System (CNS) Cancers focus on management of adult CNS cancers ranging from noninvasive and surgically curable pilocytic astrocytomas to metastatic brain disease. The involvement of an interdisciplinary team, including neurosurgeons, radiation therapists, oncologists, neurologists, and neuroradiologists, is a key factor in the appropriate management of CNS cancers. Integrated histopathologic and molecular characterization of brain tumors such as gliomas should be standard practice. This article describes NCCN Guidelines recommendations for WHO grade I, II, III, and IV gliomas. Treatment of brain metastases, the most common intracranial tumors in adults, is also described.

Publisher

Harborside Press, LLC

Subject

Oncology

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