Abstract
Annotation. The purpose of the study is to investigate the features of the local manifestation and clinical course of lichen planus in the oral cavity. The relevance of the mentioned problem is due to the growing share of patients with lichen planus, the undefined etiology and pathogenesis of this disease, the lack of a single point of view on treatment tactics and the search for opportunities for more effective treatment. 21 patients who were diagnosed with lichen planus with manifestation on the mucous membrane of the oral cavity were examined. The age of the patients ranged from 28 to 57 years. The studied patients were divided into 2 groups: the first – the main one (12 patients), which received a standard treatment scheme; the second – control (9 patients) included patients who received an etiopathogenetic treatment scheme with the inclusion of appropriate drugs. All patients underwent clinical examinations of the manifestation of the local status in the form of an assessment of pain, hyperemia, swelling, in points as follows: 1 point – no sign, 2 – slightly expressed, 3 – expressed, 4 - significantly expressed. As a result of observing the manifestations of the primary impression elements in the oral cavity, the following results were obtained. In the group of patients who received standard treatment, the healing of the primary elements of the impression of lichen planus had significantly less positive dynamics, in contrast to the group of patients who received the proposed treatment scheme. All local manifestations of the impression elements on the mucous membrane of the tongue, cheeks, and lips, which were taken into account during the examination, showed a significantly positive effect of the proposed treatment on the local signs of healing of the impression elements of the oral mucosa in lichen planus red (p<0.05). Analyzing the obtained indicators of the clinical manifestation of pain, hyperemia, swelling of the mucous membrane of the oral cavity of the patients, their positive dynamics and synchronicity are noticeable in patients of both groups. In case of lichen planus of the mucous membrane of the oral cavity, local clinical manifestations have significantly positive dynamics when using the proposed etiopathogenetic scheme of treatment (p<0.05). It was revealed that the treatment of lichen planus should be complex and etiopathogenetic, which should combine general and local treatment. The proposed etiopathogenetic scheme of treatment will reduce the recovery time of patients with lichen planus of the oral cavity by 4-5 days and improve the social adaptation of patients.
Publisher
Vinnytsia National Pyrogov Memorial Medical University
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