Author:
Tang Yue-Yang,Zhu Gui-Quan,Zheng Zhi-Jian,Yao Li-Hong,Wan Zi-Xin,Liang Xin-Hua,Tang Ya-Ling
Abstract
Type 2 diabetes mellitus (T2DM), which is distinguished by increased glucose levels in the bloodstream, is a metabolic disease with a rapidly increasing incidence worldwide. Nevertheless, the etiology and characteristics of the mechanism of T2DM remain unclear. Recently, abundant evidence has indicated that the intestinal microbiota is crucially involved in the initiation and progression of T2DM. The gut microbiome, the largest microecosystem, engages in material and energy metabolism in the human body. In this review, we concentrated on the correlation between the gut flora and T2DM. Meanwhile, we summarized the pathogenesis involving the intestinal flora in T2DM, as well as therapeutic approaches aimed at modulating the gut microbiota for the management of T2DM. Through the analysis presented here, we draw attention to further exploration of these research directions.
Publisher
Baishideng Publishing Group Inc.
Reference21 articles.
1. Tarsitano A, Pizzigallo A, Giorgini F, Marchetti C. Giant pleomorphic adenoma of the parotid gland: an unusual case presentation and literature review. Acta Otorhinolaryngol Ital 2015; 35: 293-296
2. Salivary Carcinosarcoma: An Extremely Rare and Highly Aggressive Malignancy
3. Carcinoma ex-pleomorphic adenoma of mandible: A case report and review of literature
4. Kirklin JW, McDonald JR, Harrington SW, New GB. Parotid tumors; histopathology, clinical behavior, and end results. Surg Gynecol Obstet 1951; 92: 721-733
5. Carcinosarcoma of the Parotid Gland: Report of a Case with Immunohistochemical Findings