Ca2+ Signaling in the Inner Ear

Author:

Mammano Fabio123,Bortolozzi Mario1,Ortolano Saida13,Anselmi Fabio2

Affiliation:

1. Istituto Veneto di Medicina Molecolare, Fondazione per la Ricerca Biomedica Avanzata, Padova;

2. Centro Interdipartimentale per lo Studio dei Segnali Cellulari, and

3. Dipartimento di Fisica “G.Galilei”, Università di Padova, Padova, Italy

Abstract

The inner ear contains delicate sensory receptors that have adapted to detect the minutest mechanical disturbances. Ca2+ ions are implicated in all steps of the transduction process, as well as in its regulation by an impressive ensemble of finely tuned feedback control mechanisms. Recent studies have unveiled some of the key players, but things do not sound quite right yet.

Publisher

American Physiological Society

Subject

Physiology

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