Changes in the fecal gut microbiome of home healthcare patients with disabilities through consumption of malted rice amazake

Author:

Kageyama Suzumi1ORCID,Inoue Rikako23ORCID,Park Jonguk4ORCID,Hosomi Koji3ORCID,Yumioka Hitomi35,Suka Tomo6,Teramoto Kazuaki6,Syauki A. Yasmin17,Doi Miki1ORCID,Sakaue Haruka1,Miyake Miyuu1,Mizuguchi Kenji48ORCID,Kunisawa Jun3ORCID,Irie Yasuyuki2ORCID

Affiliation:

1. Graduate School of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan

2. Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan

3. Microbial Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan

4. Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan

5. Faculty of Nutrition, Osaka Seikei College, Osaka, Japan

6. Kishu Rehabilitation Visiting Care Station, Wakayama, Japan

7. Department of Nutrition, Faculty of Medicine, Hasanuddin University, Kota Makassar, Indonesia

8. Institute for Protein Research, Osaka University, Osaka, Japan

Abstract

The consumption of malted rice amazake (MR-Amazake) showed significant changes in the gut microbiome according to principal coordinate analysis in some home healthcare patients with disabilities, including those with severe motor and intellectual disabilities. After discontinuation of intake, the gut microbiome returned to its original state. This is the first pilot study to examine both the changes in the gut microbiome and their sustainability after MR-Amazake intake.

Funder

Okayama Prefectural University

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Ministry of Health, Labour and Welfare

Publisher

American Physiological Society

Subject

Genetics,Physiology

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