COVID-19 and olfactory dysfunction: a looming wave of dementia?-Reference-Cited by-同舟云学术

COVID-19 and olfactory dysfunction: a looming wave of dementia?

Published:2022-08-01 Issue:2 Volume:128 Page:436-444
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Kay Leslie M.¹^ORCID

Affiliation:

1. Institute for Mind and Biology, Department of Psychology, The University of Chicago, Chicago, Illinois

Abstract

More than 15 million people worldwide experience persistent COVID-19 olfactory dysfunction, possibly caused by olfactory bulb damage. SARS-CoV-2 can cause inflammation and viral invasion of the olfactory bulb, initiating a cascade of degeneration similar to Alzheimer’s disease and Lewy body disease. People who have had even mild cases of COVID-19 show signs of degeneration in cortical areas connected with the olfactory system. These data suggest a wave of post-COVID dementia in the coming decades.

Funder

University of Chicago

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

Link

https://journals.physiology.org/doi/pdf/10.1152/jn.00255.2022

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2. More Than Smell—COVID-19 Is Associated With Severe Impairment of Smell, Taste, and Chemesthesis

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