1. Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania;
2. Department of Pharmaceutical Sciences, Jefferson School of Pharmacy, Thomas Jefferson University, Philadelphia, Pennsylvania;
3. Department of Physiology, Temple University School of Medicine, Philadelphia, Pennsylvania;
4. Department of Biochemistry, Temple University School of Medicine, Philadelphia, Pennsylvania; and
5. Center for Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania