Physiological characterization of gastric emptying using high-resolution antropyloroduodenal manometry

Author:

Soliman Heithem12ORCID,Wuestenberghs Fabien13,Desprez Charlotte1,Leroi Anne-Marie1,Melchior Chloé4ORCID,Gourcerol Guillaume1ORCID

Affiliation:

1. Department of Physiology, Université Rouen Normandie, INSERM, ADEN UMR1073, “Nutrition, Inflammation and Microbiota-Gut-Brain Axis,” CHU Rouen, Rouen, France

2. Department of Gastroenterology, Université de Paris-Cité, Hôpital Louis Mourier, Colombes, France

3. Department of Gastroenterology, Hôpital Avicenne, Sorbonne Paris Nord University, Bobigny, France

4. Department of Gastroenterology, Université Rouen Normandie, INSERM, ADEN UMR1073, “Nutrition, Inflammation and Microbiota-Gut-Brain Axis,” CHU Rouen, Rouen, France

Abstract

High-resolution antropyloroduodenal manometry (HR-ADM) allows precise characterization of antral, pyloric, and duodenal motility, although its association with gastric emptying (GE) has been poorly investigated. Concurrent HR-ADM with GE measurement showed a lower frequency of antral postprandial contractions and an increased frequency of postprandial pylorospasms in patients with delayed GE. HR-ADM could, therefore, be useful in the future to better select patients for treatments targeting the pylorus.

Publisher

American Physiological Society

Subject

Physiology (medical),Gastroenterology,Hepatology,Physiology

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