Affiliation:
1. Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida and
2. Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida
Abstract
Animal models of pancreatitis are useful for elucidating the pathogenesis of pancreatitis and developing and testing novel interventions. In this review, we aim to summarize the most commonly used animal models, overview their pathophysiology, and discuss their strengths and limitations. We will also briefly describe common animal study procedures and refer readers to more detailed protocols in the literature. Although animal models include pigs, dogs, opossums, and other animals, we will mainly focus on rodent models because of their popularity. Autoimmune pancreatitis and genetically engineered animal models will be reviewed elsewhere.
Funder
DOD | Congressionally Directed Medical Research Programs (CDMRP)
HHS | National Institutes of Health (NIH)
NIH-NCI
Publisher
American Physiological Society
Subject
Physiology (medical),Gastroenterology,Hepatology,Physiology
Cited by
35 articles.
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