Untargeted metabolomic profiling identifies serum metabolites associated with type 2 diabetes in a cross-sectional study of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study-Reference-Cited by-同舟云学术

Untargeted metabolomic profiling identifies serum metabolites associated with type 2 diabetes in a cross-sectional study of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

Published:2023-02-01 Issue:2 Volume:324 Page:E167-E175
ISSN:0193-1849
Container-title:American Journal of Physiology-Endocrinology and Metabolism
language:en
Short-container-title:American Journal of Physiology-Endocrinology and Metabolism

Author:

Liu Yuzhao¹,Gan Lu²,Zhao Bin²^ORCID,Yu Kai³,Wang Yangang¹,Männistö Satu⁴,Weinstein Stephanie J.³,Huang Jiaqi²⁵^ORCID,Albanes Demetrius³

Affiliation:

1. Department of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao, China

2. National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China

3. Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Bethesda, Maryland

4. Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland

5. Xiangya School of Public Health, Central South University, Changsha, China

Abstract

These metabolomic patterns may provide new additional evidence and potential insights relevant to the molecular basis of insulin resistance and the etiology of T2D.

Funder

Foundation for Innovative Research Groups of the National Natural Science Foundation of China

Outstanding Young Investigator Award of Hunan Province

HHS | NIH | National Cancer Institute

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology,Endocrinology, Diabetes and Metabolism

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpendo.00287.2022

Reference67 articles.

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5. Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: Results from the Nurses' Health Study