The metabolic benefits of substituting sucrose for maple syrup are associated with a shift in carbohydrate digestion and gut microbiota composition in high-fat high-sucrose diet-fed mice

Author:

Morissette Arianne12,André Diana Majolli12,Agrinier Anne-Laure12,Varin Thibault V.2,Pilon Geneviève1,Flamand Nicolas13,Houde Vanessa P.1,Marette André12ORCID

Affiliation:

1. Department of Medicine, Faculty of Medicine, Québec Heart and Lung Institute, Université Laval, Pavilion Marguerite d’Youville, Québec City, Québec, Canada

2. Institute of Nutrition and Functional Foods (INAF), Université Laval, Québec City, Québec, Canada

3. Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health (CERC-MEND), Université Laval, Québec City, Québec, Canada

Abstract

The natural sweetener maple syrup has sparked much interest as an alternative to refined sugars. This study aimed to investigate whether the metabolic benefits of substituting sucrose with an equivalent dose of maple syrup could be linked to changes in gut microbiota composition and digestion of carbohydrates in obese mice. We demonstrated that maple syrup is less detrimental than sucrose on metabolic health and possesses a prebiotic-like activity through novel gut microbiota and liver mechanisms.

Funder

Producteurs et productrices acericoles du Quebec

Gouvernement du Canada | Canadian Institutes of Health Research

J.A. DeSève Foundation

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology,Endocrinology, Diabetes and Metabolism

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