1. Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's and Papworth Hospitals, Cambridge, United Kingdom;
2. Department of Pharmacology, School of Pharmaceutical Science and
3. Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China;
4. Department of Rheumatology, Changzheng Hosipital, Second Military Medical University, Shanghai, China