Central sleep apnea treated by a constant low-dose CO2 supplied by a novel device

Author:

Luo Yuan-Ming123ORCID,Chen Yong-Yi1,Liang Shan-Feng1,Wu Lu-Guang1,Wellman Andrew2,McEvoy R. Doug3,Steier Joerg4,Eckert Danny J.3ORCID,Polkey Michael I.5

Affiliation:

1. State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, People’s Republic of China

2. Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States

3. College of Medicine and Public Health, Adelaide Institute for Sleep Health, Flinders University, Adelaide, South Australia, Australia

4. Lane Fox Respiratory Unit/Sleep Disorders Centre, London, United Kingdom

5. Royal Brompton Hospital, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom

Abstract

A novel device using a special mask was developed and proved that CO2 therapy using the device could eliminate central sleep apnea (CSA) events and improve sleep quality including reducing arousal index in patients with heart failure. The device would become a useful clinical treatment for heart failure patients with CSA.

Funder

Zhongnanshan Medical Foundation of Guangdong Province Grant

Zhongnanshan Medical Foundation of Guangdong Province

Guangdong Provincial Department of Science and Technology

Guangzhou Municipal Science and Technology Bureau

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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