Association of <i>MMP3</i> gene polymorphism and sex on recovery of muscle strength after eccentric exercise-Reference-Cited by-同舟云学术

Association of MMP3 gene polymorphism and sex on recovery of muscle strength after eccentric exercise

Published:2023-09-01 Issue:3 Volume:135 Page:527-533
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Deguchi Minoru¹,Homma Hiroki²,de Almeida Kathleen Y.¹,Kozuma Ayumu¹,Saito Mika¹,Tsuchiya Yosuke³,Kouzaki Karina⁴^ORCID,Ochi Eisuke⁵,Okamoto Takanobu¹²^ORCID,Nakazato Koichi¹⁴^ORCID,Kikuchi Naoki¹²^ORCID

Affiliation:

1. Graduate School of Health and Sport Science, Nippon Sport Science University, Tokyo, Japan

2. Faculty of Sport Science, Nippon Sport Science University, Tokyo, Japan

3. Laboratory of Health and Sports Sciences, Meiji Gakuin University, Kanagawa, Japan

4. Faculty of Medical Science, Nippon Sport Science University, Kanagawa, Japan

5. Faculty of Bioscience and Applied Chemistry, Hosei University, Tokyo, Japan

Abstract

Sex differences were identified in the AUC of creatin kinase (CK) and interleukin 6 (IL-6) after eccentric exercise, both of which were greater in men. A genotype-sex interaction was identified in recovery of maximal voluntary contraction (MVC). The G allele showed a significantly lower recovery of MVC than AA genotype in men. To our knowledge, this is the first study to report the interaction between MMP3 gene rs522616 polymorphism and sex difference on recovery of muscle strength after eccentric exercise.

Funder

Japan Society for the Promotion of Science

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00333.2023

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