Habituation attenuates the sex-specific associations between ischemic pain, blood pressure, and arterial stiffness in young adults

Author:

Lincoln Zoe R.1,Blumenburg Wesley T.1,Cross Brett L.1,Vondrasek Joseph D.1,Watso Joseph C.2ORCID,Flatt Andrew A.1ORCID,Linder Braxton3ORCID,Robinson Austin T.3ORCID,Grosicki Gregory J.1ORCID

Affiliation:

1. Biodynamics and Human Performance Center, Georgia Southern University, Savannah, Georgia

2. Cardiovascular and Applied Physiology Laboratory, Department of Nutrition and Integrative Physiology, Florida State University, Tallahassee, Florida

3. Neurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, Alabama

Abstract

We demonstrate sex differences in the association between pain perception and cardiovascular reactivity (CVR) during ischemic pain. We also demonstrate habituation to pain and reduced CVR during repeated exposure in a sex-independent manner. Accounting for sex differences and habituation may improve the prognostic utility of CVR.

Funder

Georgia Southern University

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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