Modeling the physiological roles of the heart and kidney in heart failure with preserved ejection fraction during baroreflex activation therapy-Reference-Cited by-同舟云学术

Modeling the physiological roles of the heart and kidney in heart failure with preserved ejection fraction during baroreflex activation therapy

Published:2022-09-01 Issue:3 Volume:323 Page:H597-H607
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Clemmer John S.¹^ORCID,Pruett W. Andrew¹

Affiliation:

1. Department of Physiology and Biophysics, Center for Computational Medicine, University of Mississippi Medical Center, Jackson, Mississippi

Abstract

Treatments that are efficacious in patients with HFrEF have not shown a significant impact on cardiovascular mortality in patients with HFpEF. We believe these simulations offer novel insight into the important roles of the cardiac and renal nerves in HFpEF and the potential mechanisms of how baroreflex activation alleviates HFpEF disease progression.

Funder

HHS | NIH | National Institute of General Medical Sciences

HHS | NIH | National Institute on Minority Health and Health Disparities

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00329.2022

Reference74 articles.

1. Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

2. Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction