Affiliation:
1. Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic
Abstract
We present the use of retrograde perfusion and optical mapping to investigate, for the first time, the regression of accessory pathways during annulus fibrosus maturation, separately examining each clinically relevant location. The system enables measurements under physiological conditions and demonstrates long-lasting stability compared with other approaches. This study offers applications of the model to investigate electrical and/or functional development in late embryonic development without concern about heart viability.
Funder
Czech Health Research Council
Charles University Cooperatio
National Institute for Research of Metabolic and Cardiovascular Diseases
Grantová Agentura České Republiky
Publisher
American Physiological Society