Time-efficient, high-resistance inspiratory muscle strength training increases cerebrovascular reactivity in midlife and older adults

Author:

Freeberg Kaitlin A.1ORCID,Craighead Daniel H.1ORCID,Heinbockel Thomas C.1,Rossman Matthew J.1ORCID,Jackman Rachel A.1,Jankowski Lindsey R.1,Ludwig Katelyn R.1,Chonchol Michel2,Bailey E. Fiona3ORCID,Seals Douglas R.1ORCID

Affiliation:

1. Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, United States

2. Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States

3. Department of Physiology, University of Arizona College of Medicine, Tucson, Arizona, United States

Abstract

Midlife/older adults with above-normal blood pressure are at increased risk of developing cognitive decline and dementia. Our findings suggest that high-resistance inspiratory muscle strength training (IMST), a novel, time-efficient (5–10 min/day) form of physical training, may increase cerebrovascular reactivity to CO2 and episodic memory in midlife/older adults with initial above-normal blood pressure.

Funder

American Heart Association

HHS | National Institutes of Health

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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