Ultrasonographic assessment of pulmonary and central venous congestion in experimental heart failure

Author:

Hegemann Niklas1234ORCID,Sang Pengchao1234,Kim Jonathan H.34,Koçana Ceren1234ORCID,Momin Noor5,Klages Jan26,Kucherenko Mariya M.1234,Knosalla Christoph124,O’Brien Benjamin2467ORCID,Simmons Szandor34ORCID,Nahrendorf Matthias5,Kuebler Wolfgang M.34ORCID,Grune Jana12345ORCID

Affiliation:

1. Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Der Charité (DHZC), Berlin, Germany

2. Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

3. Institute of Physiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Physiology, Berlin, Germany

4. German Centre for Cardiovascular Research, Berlin, Germany

5. Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States

6. Department of Cardiac Anesthesiology and Intensive Care Medicine, Deutsches Herzzentrum Der Charité, Berlin, Germany

7. William Harvey Research Institute, London, United Kingdom

Abstract

As thorough, noninvasive assessment of congestion is not available in small animals, we developed and validated an ultrasonography-based research tool to evaluate pulmonary and central venous congestion in experimental heart failure models.

Funder

Bundesministerium für Bildung und Forschung

Corona-Stiftung

Deutsche Forschungsgemeinschaft

Deutsche Gesellschaft für Kardiologie-Herz und Kreislaufforschung.

Deutsche Stiftung für Herzforschung

Deutsches Zentrum für Herz-Kreislaufforschung

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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