Consensus on targeted drug therapy for spondyloarthritis

Author:

Tian Xinping1,Li Mengtao1,Liu Shengyun2,Leng Xiaomei1,Wang Qian1,Zhao Jiuliang1,Liu Yi3,Zhao Yan1,Zhang Yizhi4,Xu Huji5,Gu Jieruo6,Zeng Xiaofeng1ORCID

Affiliation:

1. Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education , Beijing , China

2. Department of Rheumatology and Immunology, the First Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan Province , China

3. Department of Rheumatology and Immunology, West China Hospital Sichuan University , Chengdu , Sichuan Province , China

4. Department of Rheumatology and Immunology, the First Affiliated Hospital of Harbin Medical University , Haerbin , Heilongjiang Province , China

5. Department of Rheumatology and Immunology, Shanghai Changzheng Hopital , Shanghai , China

6. Department of Rheumatology and Immunology, the Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , Guangdong Province , China

Abstract

Abstract Spondyloarthritis (SpA) is a group of chronic inflammatory diseases that predominantly involve the spine and/or peripheral joints. The clinical manifestations of SpA are highly heterogenous and complicated with various comorbidities. SpA is a disabling disease and adversely affects the quality of life of patients. Many new medications that target cytokines or pathways specific for the pathogenesis of SpA have been developed and they are becoming increasingly important in the treatment of SpA. However, identifying the target patient population and standardizing the usage of these drugs are critical issues in the clinical application of these “targeted therapeutic drugs”. Under the leadership of National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), managed by Peking Union Medical College Hospital, the “Consensus on targeted drug therapy for spondyloarthritis” has been developed in collaboration with the Rheumatology and Immunology Physicians Committee, Chinese Medical Doctors Association, Rheumatology and Immunology Professional Committee, Chinese Association of Rehabilitation Medicine, and Chinese Research Hospital Association Rheumatology and Immunology Professional Committee. This consensus has been developed with evidence-based methodology and has followed the international standard for consensus development.

Publisher

Walter de Gruyter GmbH

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