Benefits of physical activity on cardiometabolic diseases in obese children and adolescents

Author:

Gao Juan12,Lu Yi1,Gokulnath Priyanka3,Vulugundam Gururaja4,Li Guoping3,Li Jin2,Xiao Junjie12

Affiliation:

1. Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People’s Hospital of Nantong), School of Medicine, Shanghai University , Nantong 226011 , Jiangsu Province , China

2. Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University , Shanghai 200444 , China

3. Cardiovascular Division of the Massachusetts General Hospital and Harvard Medical School , Boston 02114, MA , USA

4. Institute of Biochemistry and Cellular Biology, National Research Council of Italy , Napoli 80131 , Italy

Abstract

Abstract In the past few decades, obesity in the pediatric population has dramatically increased and is common in many countries. Childhood obesity often causes health problems and increases the risk of cardiometabolic diseases such as type 2 diabetes, nonalcohol fatty liver, and cardiovascular diseases. Obesity in young people has been closely associated with environmental, behavioral, and genetic defects, including the availability of high-energy and sugary food and beverages, sedentary behavior, and hereditary factors. Few drugs are currently available to treat obesity in children and adolescents because it is difficult to demonstrate the safety of these drugs on the growth and development of the youth. Lifestyle modifications, such as diet control and physical exercise, are the primary approaches for preventing and treating childhood obesity. Among them, physical activity is a crucial component. This review summarizes the epidemiology, cardiometabolic risk of obesity, therapeutic strategies, and the benefits of exercise on obesity-related chronic diseases in children and adolescents.

Publisher

Walter de Gruyter GmbH

Subject

Internal Medicine

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