Current aspects of the diagnosis and treatment of adenoid cystic carcinoma of the trachea and larynx: a literature review

Author:

Kozhanov L. G.1ORCID,Kozhanov A. L.2ORCID,Romanova E. S.3ORCID

Affiliation:

1. City Clinical Oncological Hospital No. 1, Moscow Healthсare Department; Department of Oncology and Radiation Therapy of the N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia

2. City Clinical Oncological Hospital No. 1, Moscow Healthсare Department

3. Central Clinical Hospital “RZD-Medicine”

Abstract

This review discusses current aspects of the diagnosis and treatment of adenoid cystic carcinoma of the trachea and larynx. It describes different variants of surgical treatment, radiotherapy, combination therapy, endotracheal interventions using endoscopic techniques and physical methods, grafting, tracheal transplantation, complications, and oncological and functional treatment outcomes. We also analyze clinical aspects of adenoid cystic carcinoma of the larynx, most common tumor location, difficulties associated with morphological verification, and controversial issues related to surgery volume, considering that this disease is rare and clinical experience is often insufficient.

Publisher

Publishing House ABV Press

Subject

Pharmacology (medical),Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology,Otorhinolaryngology,Surgery

Reference66 articles.

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2. Ali S., Yeo J., Magos T. et al. Clinical outcomes of adenoid cystic carcinoma of the head and neck : a single institution 20-year experience. J Laryngol Otol 2016;130(7):680–5. DOI: 10.1017/S0022215116008124.

3. Perelman M.I. Surgery of trachea. Moscow: Medicina, 1972. 220 p. (In Russ.)]. Avaliable at: https://studfile.net/preview/1215219.

4. Kharchenko V.P., Chkhikvadze V.D., Gvarishvili A.A. et al. Adenocystic tracheal cancer. Hirurgiya. Zhurnal im. N.I. Pirogova = N.I. Pirogov Zhurnal 2018;11:11–19. (In Russ.). DOI: 10.17116/hirurgia20161124-11.

5. Zhao H., Xu S., Zhang L. et al. Surgical treatment of primary tracheal adenoid cystic carcinoma:report of 11 cases. Zhonghua Jie He He Hu Xi Za Zhi 2003;26(7):400–2.

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