HYPOTHALAMIC HAMARTOMA. LITERATURE REVIEW

Author:

Grigoriev А. Yu.1ORCID,Sinkin М. V.2ORCID,Grigorieva Е. V.3ORCID,Trifonov I. S.3ORCID

Affiliation:

1. A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia; National Medical Research Center of Endocrinology, Ministry of Health of Russia

2. N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare Department

3. A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia

Abstract

The study objective is to analyze scientific literature on hypothalamic hamartomas’ diagnostics and treatment. Materials and methods. We studied 90 scientific sources, published between 1948 and 2019. Results. The paper describes clinical picture of hypothalamic hamartomas, their various classifications, specificity of neuroimaging and neurophysiological diagnostics and pathomorphological research, the surgical treatment. Conclusion. Transnasal resection is a promising and noninvasive method to treat hypothalamic hamartomas of IV and V types by J. Régis classification. According to the scientific literature, stereotactic destruction can be used to resect hamartomas of I–IV types; types II and III require endoscopic transventricular approach, while types IV and V can be resected using endoscopic transnasal transsphenoidal approach.

Publisher

Publishing House ABV Press

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Hypothalamic hamartoma dissection using focused ultrasound under MRI control. The first successful experience in Russia;Voprosy neirokhirurgii imeni N.N. Burdenko;2024

2. Hypothalamic Hamartoma as a Cause of Drug-Resistant Epilepsy in Children;Неврология и нейрохирургия. Восточная Европа;2021-03-23

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