Nephrotoxicity of combination drug therapy in metastatic renal cancer

Author:

Titov K. S.1ORCID,Shutov E. V.2ORCID,Alimov A. A.1ORCID,Lebedev S. S.2ORCID,Kirichek A. A.3ORCID,Zapirov G. M.4ORCID

Affiliation:

1. S.P. Botkin City Clinical Hospital, Moscow Healthcare Department; Peoples’ Friendship University of Russia named after Patrice Lumumba

2. S.P. Botkin City Clinical Hospital, Moscow Healthcare Department; Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia

3. S.P. Botkin City Clinical Hospital, Moscow Healthcare Department

4. Peoples’ Friendship University of Russia named after Patrice Lumumba

Abstract

The review covers reduced kidney function in the context of renal cell carcinoma. According to international studies, some patients  already have chronic kidney disease at time of disease onset. Surgical treatment  leads to a decrease in the total number of functioning nephrons. Drug therapy causes several adverse events including nephrotoxicity. The review discusses the problem of using combination regimens in patients with solitary kidney.

Publisher

Publishing House ABV Press

Subject

Urology,Nephrology,Radiology, Nuclear Medicine and imaging,Oncology,Surgery

Reference69 articles.

1. World Health Organization. The Global Cancer Observatory. Available at: https://gco.iarc.fr.

2. Malignant tumors in Russia in 2020 (morbidity and mortality). Eds.: A.D. Kaprin, V.V. Starinskiy, A.O. Shakhzadova. Moscow: MNIOI im. P.A. Gertsena - filial FGBU “NMITS radiologii” Minzdrava Rossii, 2021. 252 p. (In Russ.).

3. SEER Explorer. Available at: https://seer.cancer.gov/explorer/index.html (accessed March 2, 2020).

4. Heng D.Y., Wells J.C., Rini B. et al. Cytoreductive nephrectomy in patients with synchronous metastases from renal cell carcinoma: results from the International Metastatic Renal Cell Carcinoma Database Consortium. Eur Urol 2014;66(4):704-10. DOI: 10.1016/j.eururo.2014.05.034

5. Mejean A., Ravaud A., Thezenas S. et al. Sunitinib alone or after nephrectomy in metastatic renal-cell carcinoma. N Engl J Med 2018;379(5):417-27. DOI: 10.1056/NEJMoa1803675

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3