Effects of Methylphenidate in Normal Adults with Reference to Drug Action in Hyperactivity

Author:

Aman Michael G.1,Vamos Marina2,Werry John S.3

Affiliation:

1. Dept. of Psychiatry, School of Medicine, University of Auckland, Auckland, New Zealand

2. Adult Psychiatric Unit, Auckland Hospital

3. Department of Psychiatry, University of Auckland

Abstract

Methylphenidate was administered to each of 12 adult volunteers in a double-blind, placebo-controlled, crossover study for purposes of comparison with previous studies in hyperactive children. Statistically significant changes occurred only on a minority of measures, but the results were generally in the direction of facilitated performance, reduced physical activity and increased emotional responsivity. As these results are similar to those in hyperactive and normal children, this appears to support the contention that stimulant drug effects in hyperactive children are not paradoxical or atypical.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health,General Medicine

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