Abstract
AbstractA range of β-homoprolines was prepared with high anti-selectivity. An intramolecular C–H insertion reaction involving a rhodium alkyl nitrene is a key step in the ring construction. The carboxylic acid in the products can serve as a springboard for further downstream transformations.
Funder
Japan Society for the Promotion of Science
Takeda Science Foundation
Takahashi Industrial and Economic Research Foundation