Facilitating Genetics Aware Clinical Decision Support: Putting the eMERGE Infrastructure into Practice

Author:

Taylor Casey Overby12,Rasmussen Luke V.3,Rasmussen-Torvik Laura J.3,Prows Cynthia A.4,Dorr David A.5,Samal Lipika6,Aronson Samuel7

Affiliation:

1. Departments of Medicine and Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States

2. Geisinger Health System, Genomic Medicine Institute, Danville, Pennsylvania, United States

3. Department of Preventive Medicine, Northwestern University, Chicago, Illinois, United States

4. Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

5. Departments of Medical Informatics and Clinical Epidemiology and Medicine, Oregon Health & Science University, Portland, Oregon, United States

6. Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States

7. Partners Personalized Medicine, Partners HealthCare, Cambridge, Massachusetts, United States

Abstract

AbstractThis editorial provides context for a series of published case reports in ACI Open by summarizing activities and outputs of joint electronic health record integration and pharmacogenomics workgroups in the NIH-funded electronic Medical Records and Genomics (eMERGE) Network. A case report is a useful tool to describe the range of capabilities that an IT infrastructure or a particular technology must support. The activities we describe have informed infrastructure requirements used during eMERGE phase III, provided a venue to share experiences and ask questions among other eMERGE sites, summarized potential hazards that might be encountered for specific clinical decision support (CDS) implementation scenarios, and provided a simple framework that captured progress toward implementing CDS at eMERGE sites in a consistent format.

Funder

National Human Genome Research Institute

Cincinnati Children's Hospital Medical Center

Publisher

Georg Thieme Verlag KG

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