Ultrasound Elastography for Characterization of Focal Liver Lesions

Author:

Dong Yi12,Koch Jonas3,Alhyari Amjad4,Safai Zadeh Ehsan4ORCID,Görg Christian4,Wang Wen-Ping1,Berzigotti Annalisa5,Dietrich Christoph F.3ORCID

Affiliation:

1. Department of Ultrasound, Zhongshan Hospital Fudan University, Shanghai, China

2. Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

3. Department Allgemeine Innere Medizin, Kliniken (DAIM) Hirslanden Beau Site, Salem und Permanence, Bern, Switzerland

4. Interdisciplinary Center of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Gastroenterology, Endocrinology, Metabolism and Clinical Infectiology, Philipps University Marburg, Marburg, Germany

5. Department of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Berne, Switzerland

Abstract

AbstractFocal liver lesions (FLL) are typically detected by conventional ultrasound or other imaging modalities. After the detection of FLL, further characterization is essential, and this can be done by contrast-enhanced imaging techniques, e.g., contrast-enhanced ultrasound (CEUS) and magnetic resonance imaging (MRI) or by means of biopsy with histological evaluation. Elastographic techniques are nowadays integrated into high-end ultrasound systems and their value for the detection of severe liver fibrosis and cirrhosis has been shown in studies and meta-analyses. The use of an ultrasound elastographic technique for the differentiation of malignant and benign liver tumors is less well-established. This review summarizes the current data on utility and performance of ultrasound elastography for the characterization of FLL.

Funder

National Natural Science Foundation of China

Shanghai Pujiang Program

Clinical Research Plan of SHDC

Publisher

Georg Thieme Verlag KG

Subject

Gastroenterology

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