Pivotal Reactions in the Creation of the Polycyclic Skeleton of Cryptotrione

Author:

Wong Henry N. C.12,Peng Xiao-Shui12ORCID,Zhong Zhuliang2,Lyu Mao-Yun2,Ma Hao-Ran1

Affiliation:

1. School of Science and Engineering, The Chinese University of Hong Kong (Shenzhen)

2. Department of Chemistry, and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong

Abstract

AbstractThree pivotal reactions, namely, enyne cycloisomerization, polyene cyclization, and quinone methide formation, are applied to synthesize the complex polycyclic skeleton of cryptotrione. This review summarizes the most prominent applications of these three reactions to the total syntheses of natural products, covering results published in the literature between 2011 and 2020.1 Introduction2 Three Pivotal Reactions Applied to Create the Polycyclic Framework of Cryptotrione2.1 Enyne Cycloisomerization2.2 Polyene Cyclization2.3 Quinone Methide Formation3 Conclusion

Funder

National Natural Science Foundation of China

Research Grants Council, University Grants Committee

Innovation and Technology Commission - Hong Kong

Impact Postdoctoral Fellow Scheme

Chinese University of Hong Kong

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

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