Case Report with a Review of Literature: Pancoast Syndrome—A Rare Presentation of Metastatic Hepatocellular Carcinoma

Author:

Singuluri Lakshmi Sandhya1ORCID,Ganesan Prasanth1ORCID,Srinivas Bheemanathi Hanuman2,Dubashi Biswajit1ORCID,Nisha Yadav1

Affiliation:

1. Department of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India

2. Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India

Abstract

AbstractSuperior sulcus tumors, also known as Pancoast tumors, present in a distinctive way with Horner's syndrome (ptosis, miosis, and anhidrosis), hand weakness brought on by the atrophy of the intrinsic hand muscles, and excruciating pain along the medial aspect of the arm. (1) Primary lung cancers constitute a majority of Pancoast tumors, but Pancoast syndrome can be multifactorial. (2) Here, we present a case of 62-year-old male who presented with right shoulder pain and weakness for 2 months. Clinically, he had a supraclavicular mass with atrophy of the intrinsic muscles of the hand and sensory-motor weakness. Computed tomography showed a mass lesion in the supraclavicular fossa with the erosion of the T1 vertebra and first rib, mimicking carcinoma right upper lobe. However, the biopsy from the mass was suggestive of metastasis from hepatocellular carcinoma (HCC). Our case report identifies HCC as a rare differential for Pancoast syndrome and highlights the unique metastatic presentation.

Publisher

Georg Thieme Verlag KG

Subject

Oncology,Pediatrics, Perinatology and Child Health

Reference22 articles.

1. Superior sulcus (Pancoast) tumors: current evidence on diagnosis and radical treatment;C N Foroulis;J Thorac Dis,2013

2. Pancoast tumors: characteristics and preoperative assessment;N Panagopoulos;J Thorac Dis,2014

3. Pancoast syndrome caused by metastasis to the superior mediastinum of hepatocellular carcinoma;J J Hung;Thorac Cardiovasc Surg,2007

4. Superior pulmonary sulcus tumor: tumor characterized by pain, Horner's syndrome, destruction of bone and atrophy of hand muscles Chairman's address;H K Pancoast;J Am Med Assoc,1932

5. Clinical features of hepatocellular carcinoma: review of 211 patients in Hong Kong;C L Lai;Cancer,1981

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